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N-Desmethyltamoxifen hydrochloride - CAS# 15917-65-4 0273 16837-52-8

SKU: 54246334177

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Description

16837-52-8

PubMed PMID: 23934191

GSK0660 blocks the TNFα-induced upregulation of CCL8

PubMed Central PMCID: PMC1567301

Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells

N-Desmethyltamoxifen hydrochloride - CAS# 15917-65-4 0273 16837-52-8N Desmethyltamoxifen hydrochloride, CAS No. 15917 65 4, is the major metabolite of tamoxifen in humans. N Desmethyltamoxifen, a poor antiestrogen, is a ten fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. Product information CAS Number: 15917 65 4

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